December 20th, 2011

Last A1c Tuesday December 20th, 2011: 7.2%.

Same deal. We are with a lot of basal (about 2U/kgrm), normal corrections (1U per 15 grams of carbs), and by the way he eats (no diet so far), we are always expecting A1c to go through the roof.

September 20th, 2011

Last A1c Friday September 16th, 2011: 7.6%.

We had a rough trimester, with values all too often between 200 to 300. Eventually we had to increase the basals a lot from 91U a day in June, to 127 right now. That's 2 U/kgrm. Now we are back to the 100-200 range. As usual, I thought that A1c would be way higher, as the BG 90 day average was giving 8% for A1c.

By the way, I've started to use www.diabase.co to keep the values, make the graphics, etc.

June 11th, 2011

Last A1c: 7.0% I'll say that I was expecting a way higher one. The averages with the meter were consistently high, we had to increase basal insulin by the week. Last blog the daily dose was 67 (day) and 5 (night), and now we are at 78 (day) and 12 (night). Growth is about 1/2" a month. Clothing is lasting just a couple of months!

March 20th, 2011

Just on update on values:

A1c in January 10th, 2011, was 7.3% (from 6.8% last). Let's add that this was after a huge vacation feasting on junk food.

So after we went back to normal meals, A1c in March 20th, 2011 was 6.3%. No big restrictions, just normal meals at home, eyeballing the corrections.

NPH is at a total of 67 units for the day, 5 units for the night. Age is 12, weight is 50kg (110 lbs), height 1.50 mtrs (59 inches). That's about 1.5 Units per kgrm.

I'm sure those following the blog knew that in August 2010 Lilly and Macrogenics announced the suspension of the trials because the low efficacy of the drug. They also added that there were not unanticipated safety issues.

As someone put it, results were not terrific in the vast majority of the patients. Unfortunately, so far results for the star patients were not released, neither a paper with the results of this particular trial.

There's now another trial ( http://clinicaltrials.gov/ct2/show/NCT01030861 ) to see if the drug is able to prevent or delay the onset of diabetes in relatives at risk. I'm glad to hear that, because if there were safety issues -yes, I know, they've said there were none unanticipated-, I think we would not see another trial.

I'll keep posting A1c every 3 months and any dramatic change in anything, for example diet.

If you look at all the previous posts, diet has been from lousy to normal all this time, which is great, as the boy can go to a birthday party (with a preload of insulin), and eat the same as everyone else's. The only precaution is to take diet sodas.

So long folks!

Sept 20th, 2010

Now the trial is over. So let's just look at the figures of this quarter:

week 3 September 10:
BG 90 days average: 160.1 - A1c from BG: 7.3% - A1c from lab test: 6.8%
Total BG tests: 489 - 90 days average: 5.4 tests a day
Bolus insulin shots: 338 - 90 days average: 3.7 shots a day
Average Bolus corr. per day: 15.2 units x 15 = 228 grms Carbs per day
NPH insulin total units per day average: 50.4

You may notice that in previous posts the "horrible" periods were with BG 160-180. Now the bad period was about 200. As usual, a bit slow to catch up with the slow insulin (NPH). There was some growth (1/2" a month). In that period, we went up with the DAY dose of NPH (from 36 to 44), but the night dose, went down from 16 to 6, even 4 some days.

Anyway, besides that, no thrills as usual, no illness. In the near future I'll make a table with the values quarter by quarter, and I keep filling it up. I'll consolidate also the graphs for full years.

Week 113, June 21st, 2010

And that was it! Trial is now over, the 2 years now elapsed. We cannot say right now if we are going to take part in the follow-up extension (3 more years, 2 controls a year), but I plan to keep posting the A1c and BG values as I have done it so far. Later on perhaps I'll summarize on our impressions, but all in all we have not sweated with diet, and we did yes all the needed corrections. We've been measuring BG more in this last stretch as we had some stubborn days. Some told me that they were growth spurs. Other than that, no changes from the previous posts. Thanks to all that followed the blog, you've been a most graceful public. Yet, keep watching the page, I'll be posting values every 3 months, and of course any other news of interest.

Figures:

week 3 June 10:
BG 90 days average: 139.1 - A1c from BG: 6.6% - A1c from lab test: 6.7%
Total BG tests: 583 - 110 days average: 5.3 tests a day
Bolus insulin shots: 375 - 110 days average: 3.4 shots a day
Average Bolus corr. per day: 13 units x 15 = 195 grms Carbs per day
NPH insulin total units per day average: 38.3

week 1 March 10:
BG 90 days average: 132.1 - A1c from BG: 6.4% - A1c from lab test: 6.8%
Total BG tests: 443 - 90 days average: 4.9 tests a day
Bolus insulin shots: 296 - 90 days average: 3.3 shots a day
Average Bolus corr. per day: 11.9 units x 15 = 178 grms Carbs per day
NPH insulin total units per day average: 34.0

Week 97, Mar 1st, 2010

Figures:

week 1 March 10:
BG 90 days average: 132.1 - A1c from BG: 6.4% - A1c from lab test: 6.8%
Total BG tests: 443 - 90 days average: 4.9 tests a day
Bolus insulin shots: 296 - 90 days average: 3.3 shots a day
Average Bolus corr. per day: 11.9 units x 15 = 178 grms Carbs per day
NPH insulin total units per day average: 34.0

week 2 December 09:
BG 90 days average: 130.3 - A1c from BG: 6.3% - A1c from lab test: 6.4%
-That's correct, ONE point down-
Total BG tests: 477 - 90 days average: 5.3 tests a day
Bolus insulin shots: 265 - 90 days average: 2.9 shots a day
Average Bolus corr. per day: 10.9 units x 15 = 163 grms Carbs per day
NPH insulin total units per day average: 30.4